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Thread: is life evolved chemical tetris?

  1. #1
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    is life evolved chemical tetris?

    Organic chemistry differs from inorganic in terms of structural and spatial complexity. Many enzymatic reactions resemble legos. How can this 3D heterogeneity impact non equillibrium, add to evolution, etc?

  2. #2
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    By resembling Legos, you mean, the associated diagram reminds you of the plug-and-fit of Lego blocks?

  3. #3
    Quote Originally Posted by globali View Post
    Organic chemistry differs from inorganic in terms of structural and spatial complexity. Many enzymatic reactions resemble legos. How can this 3D heterogeneity impact non equillibrium, add to evolution, etc?
    I can't remember where I heard this but proteins fold onto on another like pieces of a jigsaw puzzle and researchers have found the only way to do this is that they evolved together at the same time.
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  4. #4
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    Here is a recent (November 2017) theoretical model for the origin of protein folding.

  5. #5
    Quote Originally Posted by Colin Robinson View Post
    Here is a recent (November 2017) theoretical model for the origin of protein folding.
    I think that is what I was think about.
    From the wilderness to the cosmos.
    You can not be afraid of the wind, Enterprise: Broken Bow.
    https://davidsuniverse.wordpress.com/

  6. #6
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    Protein-first concept i think is much more convincing than RNA first!

    Note also that some mutations can alter the stereospecificity toward the ligand making the receptor promiscuous. A classic example is in cancer, as a way to escape therapy and allow a subset of clones to continue growing

  7. #7
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    Way cool animation of DNA replication.

    https://imgur.com/gallery/xwSNX

    DNA.jpg

  8. #8
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    you might find this interesting!!

    Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA, Nature Chemistry (2018). nature.com/articles/doi:10.1038/s41557-018-0018-7

    https://phys.org/news/2018-04-biomim...viral.html#jCp

  9. #9
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    I wonder about vorticity. Smokers with tides washing bck and forth--vortlets spawning off...etc.

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