An interesting way to use the 20 meter circular capability. I might have thought of an aeroshell & possibly EOR with a bigger Tuna Can hab as from Mars Direct (or asteroid missions -centripetal artificial G is a necessity for us to develop).
They show the primary hull saucer section as the center for a bigger structure & mirror for a space telescope/antennae array.
Figure 14., the Ultimate Launch System is perhaps the most sensible use of the Shuttle hardware. Existing vehicle processing and launch facilities, if held to two LRBs. Something like the Shuttle-C/Side-Mount should have been flying since the early '80s.