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Thread: Cannabinoids and Neurogenesis Study

  1. #1
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    Cannabinoids and Neurogenesis Study

    October 13, 2005
    "Abstract
    ...We show that both embryonic and adult rat hippocampal NS/PCs are immunoreactive for CB1 cannabinoid receptors, indicating that cannabinoids could act on CB1 receptors to regulate neurogenesis..."
    Full .pdf article
    2005 by the American Society for Clinical Investigation

  2. #2
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    Interesting research!
    But please note -- the rats got it by injection. not inhalation

  3. #3
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    Saw it in Science News. Interesting stuff... Perhaps cannabinoids will find future use in the long-term treatment of clinical depression.

  4. #4
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    Hmmh...from another study
    ...Abstract
    Cannabis smoke contains cannabinoids whereas tobacco smoke contains nicotine. Available scientific data, that examines the carcinogenic properties of inhaling smoke and its biological consequences, suggests reasons why tobacco smoke, but not cannabis smoke, may result in lung cancer...Harm Reduction Journal

  5. #5
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    Cannabis smoke contains cannabinoids
    Duh.

    Available scientific data, that examines the carcinogenic properties of inhaling smoke and its biological consequences, suggests reasons why tobacco smoke, but not cannabis smoke, may result in lung cancer...
    Not correct, sorry. Pot may not be as addictive as tobacco, but it can still mess up your lungs if you smoke it. If cannabinoids are to be used to treat depression, some other form of delivery would be very much preferable.

    (News: smoking anything will harm your lungs. Sure, nicotine has its own rather unique effect on proteins, but most of the damage comes from combustion products.)

  6. #6
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    Quote Originally Posted by Gullible Jones
    ...Not correct, sorry...
    Then how did it get published?

  7. #7
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    Quote Originally Posted by sarongsong
    Hmmh...from another study
    Quote:[...] suggests reasons why tobacco smoke, but not cannabis smoke, may result in lung cancer...Harm Reduction Journal
    From the article:
    It is possible that as the cannabis-consuming population ages, the long-term consequences of smoking cannabis may become more similar to what is observed with tobacco. However, current knowledge does not suggest that cannabis smoke will have a carcinogenic potential comparable to that resulting from exposure to tobacco smoke.
    Do get back to us when they do a study on people who smoke 2 or 3 packs of joints a day for 40 years.
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    Skepticism enables us to distinguish fancy from fact, to test our speculations. --Carl Sagan

  8. #8
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    Off-topic: I've tried Cannabis twice separated by a period of 10 years. Each time, it gave me a headache and I fell asleep.

  9. #9
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    Outside of the smoking-lung damage. I have a very good friend who has clinically diagnosed marijuana induced depression (along with psychosis and paranoia). So it isn't all laughs and late night trips to 7/11 ... not all good news.

  10. #10
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    Smile

    Quote Originally Posted by 01101001
    ...Do get back to us when they do a study on people who smoke 2 or 3 packs of joints a day for 40 years.
    Good luck finding subjects who can do that for one day, much less 40 years.

  11. #11
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    Quote Originally Posted by sarongsong
    Good luck finding subjects who can do that for one day, much less 40 years.
    Exactly.
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    Skepticism enables us to distinguish fancy from fact, to test our speculations. --Carl Sagan

  12. #12
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    I was involved in a discussion once wherein someone said their friends smoked marijuana because it's better for you than tobacco. Of course, I'm not qualified to discuss the medical findings--I don't know them, because I won't smoke either ever--but I did have a question.

    Why smoke at all? No matter what smoke you inhale--and I've sat around many a campfire in my time--it's bad for your lungs. I mean, even the smokers I know aren't exactly thrilled when the wind sends a big burst of campfire smoke in their faces. Inhaling anything other than air reduces your oxygen absorption, at least for that breath, which sure isn't good for you.

    Now. If cannabinoids can help with my depression, vaya con dios. However, I still won't take 'em if the only way you can is smoking. (I have an appointment with a shrink next Thursday, so we'll see, right?)
    _____________________________________________
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    "Now everyone was giving her that kind of look UFOlogists get when they suddenly say, 'Hey, if you shade your eyes you can see it is just a flock of geese after all.'"

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  13. #13
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    Quote Originally Posted by Gillianren
    ...I still won't take 'em if the only way you can is smoking...
    December 13, 2005
    "Researchers have discovered a new drug that raises the level of endocannabinoids--the 'brain's own cannabis'--providing anti-depressant effects...study suggests the new drug, called URB597, might represent a safer alternative to use of marijuana for treatment of pain and depression, and open the door to new and improved treatments..."
    Last edited by sarongsong; 2006-Jan-31 at 10:08 AM.

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